A Fan . hel . Electrical Impe . ance Myography Probe for the Assessment of Neuromuscular Disease
نویسندگان
چکیده
Electrical Impe.ance Myography 5EIM6 is a nonin9asi9e, painless clinical techni;ue for the .iagnosis an. monitoring of a 9ariety of neuromuscular .iseases inclu.ing amyotrophic lateral sclerosis an. focal ner9e in>uries? It in9ol9es the application of a lo@-intensity alternating current to a muscle group an. the measurement of the conse;uent surface 9oltage patterns? This paper presents a system for the rapi. an. accurate ac;uisition of .ata employing an interrogating signal compose. of multiple tones @ith fre;uencies bet@een 10 kFz an. 4 MFz? The use of this composite signal makes possible measurement of impe.ance at multiple fre;uencies simultaneously? In a..ition, this system takes impe.ance measurements at multiple orientations @ith respect to the muscle fibers by means of an electronically reconfigurable electro.e array an. utilizes the linearity of muscle tissue to re.uce the re;uire. measurement time? Testing of the EIM system on beef has establishe. the capability of this system to rapi.ly .etect the anisotropic con.ucti9e properties of muscle tissue at multiple fre;uencies?
منابع مشابه
A Reconfigurable Electrode Array for Use in Rotational Electrical Impedance Myography
This thesis describes the design of a novel handheld electrode probe and measurement system for use in rotational electrical impedance myography (EIM), which is a method for diagnosing neuromuscular disease. The probe can be controlled from a PC via USB and uses an array of small electrode cells that can be connected together into larger electrodes with the help of crosspoint switches. A measur...
متن کاملA Technique for Performing Electrical Impedance Myography in the Mouse Hind Limb: Data in Normal and ALS SOD1 G93A Animals
OBJECTIVE To test a method for performing electrical impedance myography (EIM) in the mouse hind limb for the assessment of disease status in neuromuscular disease models. METHODS An impedance measuring device consisting of a frame with electrodes embedded within an acrylic head was developed. The head was rotatable such that data longitudinal and transverse to the major muscle fiber directio...
متن کاملElectrical impedance myography for the assessment of children with muscular dystrophy: a preliminary study.
Electrical impedance myography (EIM) provides a non-invasive approach for quantifying the severity of neuromuscular disease. Here we determine how well EIM data correlates to functional and ultrasound (US) measures of disease in children with Duchenne muscular dystrophy (DMD) and healthy subjects. Thirteen healthy boys, aged 2-12 years and 14 boys with DMD aged 4-12 years underwent both EIM and...
متن کاملElectrical impedance myography: Background, current state, and future directions.
Electrical impedance myography (EIM) is a non-invasive technique for the evaluation of neuromuscular disease that relies upon the application and measurement of high-frequency, low-intensity electrical current. EIM assesses disease-induced changes to the normal composition and architecture of muscle, including myocyte atrophy and loss, edema, reinnervation, and deposition of endomysial connecti...
متن کاملA portable system for the assessment of neuromuscular diseases with electrical impedance myography.
PRIMARY OBJECTIVE To create a system for the acquisition of multi-angle, multifrequency muscle impedance data. RESEARCH DESIGN Device development and preliminary testing. METHODS AND PROCEDURES The system presented here employs an interrogating signal composed of multiple tones with frequencies between 10 kHz and 300 kHz. The use of a composite signal makes possible measurement of impedance...
متن کامل